Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (N-Term) Peptide
PPIA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN982061
Quick Overview for Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (N-Term) Peptide (ABIN982061)
Target
PPIA
(Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PPIA antibody (Catalog #: ARP51353_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 143-155) peptide (Ovalbumin)
PPIA Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
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Background
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PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397
Protein Interaction Partner: E2F4,CD99,RB1,env,nef,vif,BSG,CD99,ITK,JAK2,PPIA,PPP3R1,PRLR,PRR13,PRSS23,PTPRN,RB1,S100A8,SUPT5H,ITK,JAK2,N,PPP3CA,PPP3R1,PRLR,PRR13,PRSS23,S100A8,Supt5h,YY1
Protein Size: 165 -
Molecular Weight
- 18 kDa
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Gene ID
- 5478
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NCBI Accession
- NM_021130, NP_066953
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UniProt
- P62937
Target
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