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Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) Peptide

PPIA Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN982060
  • Target See all PPIA products
    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PPIA antibody (Catalog #: ARP51352_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
    Synonyms
    Cyp1 Peptide, PPIA-2 Peptide, fa93g09 Peptide, ppia Peptide, wu:fa93g09 Peptide, wu:fb05e11 Peptide, wu:fb13h02 Peptide, wu:fb15a05 Peptide, CYPA Peptide, CypA Peptide, Cypa Peptide, CYPH Peptide, CYCA Peptide, CyP-A Peptide, MGC75715 Peptide, 2700098C05 Peptide, Cphn Peptide, CyP-18 Peptide, MT-ND1 Peptide, MTND1 Peptide, NADH1 Peptide, ND1 Peptide, cypA Peptide, PPIase A Peptide, ppial Peptide, wu:fj18g05 Peptide, zgc:73102 Peptide, zgc:86688 Peptide, peptidylprolyl isomerase A Peptide, peptidylprolyl isomerase Aa (cyclophilin A) Peptide, peptidylprolyl isomerase A (cyclophilin A) L homeolog Peptide, cyclophilin A Peptide, cyclophilin a Peptide, peptidylprolyl isomerase A (cyclophilin A) Peptide, peptidylprolyl isomerase Ab (cyclophilin A) Peptide, PPIA Peptide, ppiaa Peptide, ppia.L Peptide, Cypa Peptide, CNB01230 Peptide, CNB01290 Peptide, Tc00.1047053506925.300 Peptide, Tb11.03.0250 Peptide, CYPA Peptide, Ppia Peptide, ppia Peptide, ppiab Peptide
    Background
    PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.

    Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397

    Protein Interaction Partner: E2F4,CD99,RB1,env,nef,vif,BSG,CD99,ITK,JAK2,PPIA,PPP3R1,PRLR,PRR13,PRSS23,PTPRN,RB1,S100A8,SUPT5H,ITK,JAK2,N,PPP3CA,PPP3R1,PRLR,PRR13,PRSS23,S100A8,Supt5h,YY1

    Protein Size: 165
    Molecular Weight
    18 kDa
    Gene ID
    5478
    NCBI Accession
    NM_021130, NP_066953
    UniProt
    P62937
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