Protein Summary

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.

Alternative names and synonyms associated with MAPKSP1

• late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3) antibody
• late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (Lamtor3) antibody
• late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (lamtor3) antibody

• AW556229 antibody
• Map2k1ip1 antibody
• Mapbp antibody
• mapksp1 antibody
• Mp1 antibody
• Show all synonym aliases
• PRO0633 antibody
• Ragulator3 antibody
• zgc:110207 antibody

Protein level used designations for MAPKSP1

MAPK scaffold protein 1 , mitogen-activated protein kinase kinase 1 interacting protein 1 , MEK binding partner 1 , late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 , mitogen-activated protein kinase scaffold protein 1 , ragulator complex protein LAMTOR3 , MEK-binding partner 1 , mitogen activated protein, binding protein , mitogen-activated protein kinase kinase 1-interacting protein 1 , MEK partner 1 , Mitogen-activated protein kinase kinase 1-interacting protein 1 , Mitogen-activated protein kinase scaffold protein 1 , putative mitogen-activated protein kinase kinase 1 interacting protein 1