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anti-Mouse (Murine) PPP2R3C Antibodies:
anti-Human PPP2R3C Antibodies:
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findings suggest that G5PR is involved in both the survival of B cells and the differentiation of peritoneal B1a cells into autoantibody-producing plasma cells.
G5PR is required for the B cell receptor-mediated proliferation associated with the prevention of activation-induced cell death in mature B cells.
G5PR regulates the thymocyte unique apoptotic signal involved in JNK (show MAPK8 Antibodies)-mediated Caspase-3 (show CASP3 Antibodies) activation but not in Bim (show BCL2L11 Antibodies) activation.
Knockdown of PP5 (show PPP5C Antibodies) and/or PPP2R3C increased P-gp (show ABCB4 Antibodies) expression and lowered the sensitivity to vincristine and doxorubicin. Consequently, results indicate that PP5 (show PPP5C Antibodies)/PPP2R3C negatively regulates P-gp (show ABCB4 Antibodies) expression and function.
G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen.
May regulate MCM3AP phosphorylation through phosphatase recruitment. May play a role in the activation-induced cell death of B-cells (By similarity).
phosphatase subunit gene g4-1
, protein phosphatase subunit G5PR
, serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
, protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma
, rhabdomyosarcoma antigen MU-RMS-40.6A
, rhabdomyosarcoma antigen MU-RMS-40.6A/6C
, rhabdomyosarcoma antigen Mu-RMS-40.6C
, serine/threonine-protein phosphatase 2A regulatory subunit B'' gamma subunit