CARD8 Proteins
5 Caspase Recruitment Domain Family, Member 8 (CARD8) Proteins from 3 manufacturers are available on www.antibodies-online.com.
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Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-431) protein (His tag) Protein
Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-392) protein (GST tag) Protein
Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 322-431) protein (GST tag) Protein
Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 232-328) protein (GST tag) Protein
Caspase Recruitment Domain Family, Member 8 (CARD8) (AA 1-427) protein (His tag) Protein
CARD8 Protein Profile
Protein Summary
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Alternative names and synonyms associated with CARD8
- caspase recruitment domain family, member 8 (CARD8) antibody
- caspase recruitment domain-containing protein 8 (LOC718594) antibody
- caspase recruitment domain family member 8 (CARD8) antibody
- CARD8 antibody
- CARDINAL antibody
- DACAR antibody
- DAKAR antibody
- NDPP antibody
- NDPP1 antibody
- TUCAN antibody
Protein level used designations for CARD8
caspase recruitment domain family, member 8 , CARD inhibitor of NF-kappaB-activating ligands , apoptotic protein NDPP1 , caspase recruitment domain-containing protein 8 , tumor up-regulated CARD-containing antagonist of CASP9 , tumor up-regulated CARD-containing antagonist of caspase nine
GENE ID | SPECIES |
---|---|
456176 | Pan troglodytes |
718594 | Macaca mulatta |
22900 | Homo sapiens |
100172562 | Pongo abelii |
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