Browse our anti-DACT1 (DACT1) Antibodies

Full name:: anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) Antibodies (DACT1)

On www.antibodies-online.com are 39 Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) Antibodies from 11 different suppliers available. Additionally we are shipping DACT1 Proteins (3) and many more products for this protein. A total of 46 DACT1 products are currently listed.

Synonyms:: 4921528D17Rik, AI115603, dact1, DAPPER, DAPPER1, dpr, DPR1, frd1, FRODO, frodo1, HDPR1, MDpr1, MGC89695, MTNG3, RGD1564008, THYEX3, XDpr, XDpr1a

list all antibodies	Gene Name	GeneID	UniProt
	DACT1	59036	Q8R4A3
	DACT1	51339	Q9NYF0
	DACT1	500666
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Relevant Pathways for anti-DACT1 Antibodies

Positive Regulation of fat Cell Differentiation

More product categories related to DACT1 Antibody

Top referenced anti-DACT1 Antibodies

Mouse (Murine) Polyclonal DACT1 Primary Antibody for WB - ABIN2473224 : Suriben, Kivimäe, Fisher, Moon, Cheyette: Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. in Nature genetics 2009 (PubMed)

More Antibodies against DACT1 Interaction Partners

Mouse (Murine) Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) interaction partners

Dapper1 attenuates hepatic gluconeogenesis and lipogenesis in Ttype 2 diabetes.
Dpr1 promotes the ubiquitination of Dvl2 (show DVL2 Antibodies) by pVHL (show VHL Antibodies) and mediates the protein aggregate-elicited autophagy initiation
Expression analysis of Dact1-LacZ (show GLB1 Antibodies) show high expression levels in multiple mesoderm- and neuroectoderm-derived tissues during embryonic development, but restricted to a small number of postnatal tissues.
These results support a novel cell-autonomous postsynaptic role for Dact1, in cooperation with Dishevelled-1 (show DVL1 Antibodies) and possibly Disrupted in Schizophrenia-1 (show DISC1 Antibodies), in the formation of synapses on cortical interneuron dendrites.
Depletion of Dapper-1 and dishevelled-2 (show DVL2 Antibodies) in cardiomyocytes demonstrated that Dapper-1 functions upstream of dishevelled-2 (show DVL2 Antibodies) and that activity of both Dapper-1 and dishevelled-2 (show DVL2 Antibodies) is essential for activating canonical Wnt (show WNT2 Antibodies) signaling.
conserved role for Dact1 protein in kinase-regulated biochemistry involving Vangl and Dvl (show DVL1 Antibodies).
Dact1 was upregulated in the dental follicle mesenchyme at the cap stage and subsequently also in the dental papilla at the bell stage, where the expression persisted to the postnatal stages.
Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled (show DVL2 Antibodies) activity and leads to posterior malformation in mice.
This study shown that Dact1 plays an important role during dendrite and spine formation in neurons of the mammalian forebrain by promoting activation of Rac (show AKT1 Antibodies)
Frodo is expressed in primitive streak mesoderm, neuroectoderm, neural crest, presomitic mesoderm, and somites. In many cases, Frodo expression is confined to tissues undergoing extensive morphogenesis

Zebrafish Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) interaction partners

frd1 is expressed in the developing brain and mesoderm.
two Dvl (show DVL2 Antibodies)-associated paralogs, Dpr1 and Dpr2 (show DACT2 Antibodies), participate in distinct Wnt (show WNT2 Antibodies)-dependent developmental processes
target of beta-catenin (show CTNNB1 Antibodies) and/or an unknown downstream effector in development

Human Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) interaction partners

Findings suggest that the DACT1 c.1256G>A nonsense variant is causative of a specific genetic syndrome with features overlapping Townes-Brocks syndrome.
Dapper1 attenuates hepatic gluconeogenesis and lipogenesis in Ttype 2 diabetes.
An inhibitory role for DACT1 in leukemogenesis.
Dact1 is up-regulated by TGF-beta1 (show TGFB1 Antibodies), inducing apoptosis in mesangial cells.
The simultaneous methylation of DACT1 and DACT2 (show DACT2 Antibodies) may play important roles in progression of ESCC and may serve as prognostic methylation biomarkers for ESCC patients.
Dact1 has a critical role in the ability support keratinocyte proliferation, by attenuating Wnt (show WNT2 Antibodies)/beta catenin (show CTNNB1 Antibodies) signaling.
our results suggested that DACT1 was upregulated during human placenta development.
There was no statistical difference between groups concerning DACT1 and DACT2 (show DACT2 Antibodies) either in promoter hypermethylation or transcript levels. Age was associated with DACT2 (show DACT2 Antibodies) promoter hypermethylation, especially over 56 years old.
Dpr1 promotes the ubiquitination of Dvl2 (show DVL2 Antibodies) by pVHL (show VHL Antibodies) and mediates the protein aggregate-elicited autophagy initiation
Overexpression of Dapper-1 allows the translocation of MIZ-1 (show ZBTB17 Antibodies) from the nucleus to the cytoplasm.

Xenopus laevis Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) interaction partners

Dpr1 stabilizes the interaction between March2 and Dsh (show DVL2 Antibodies) in order to mediate ubiquitylation and the subsequent degradation of Dsh (show DVL2 Antibodies) protein only in the dorso-animal region of Xenopus embryo.

DACT1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with DACT1

dishevelled binding antagonist of beta catenin 1 (DACT1) antibody
dishevelled-binding antagonist of beta-catenin 1 (dact1) antibody
dishevelled binding antagonist of beta catenin 1 (dact1) antibody
dishevelled-binding antagonist of beta-catenin 1 (Dact1) antibody
dishevelled-binding antagonist of beta-catenin 1 L homeolog (dact1.L) antibody

4921528D17Rik antibody
AI115603 antibody
dact1 antibody
DAPPER antibody
DAPPER1 antibody
dpr antibody
DPR1 antibody
frd1 antibody
FRODO antibody
frodo1 antibody
HDPR1 antibody
MDpr1 antibody
MGC89695 antibody
MTNG3 antibody
RGD1564008 antibody
THYEX3 antibody
XDpr antibody
XDpr1a antibody

Protein level used designations for DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) , dapper 1 , dapper, antagonist of beta-catenin , dapper, antagonist of beta-catenin, homolog 1 , dapper homolog 1-like , dapper antagonist of catenin 1 , dapper homolog 1 , frodo homolog , thymus expressed gene 3 , thymus-expressed novel gene 3 protein , dishevelled-interacting protein , frodo 1 , hepatocellular carcinoma novel gene 3 protein , heptacellular carcinoma novel gene 3 , dapper 1-B , dapper1a , xDpr , dapper homolog 1, antagonist of beta-catenin

GENE ID	SPECIES
452938	Pan troglodytes
493325	Xenopus (Silurana) tropicalis
538778	Bos taurus
701218	Macaca mulatta
100021268	Monodelphis domestica
100339172	Oryctolagus cuniculus
100400795	Callithrix jacchus
100437942	Pongo abelii
100546955	Meleagris gallopavo
100555885	Anolis carolinensis
100606126	Nomascus leucogenys
59036	Mus musculus
405799	Danio rerio
723789	Gallus gallus
100687551	Canis lupus familiaris
51339	Homo sapiens
399186	Xenopus laevis
500666	Rattus norvegicus

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Show all anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) Antibodies with Pubmed References