anti-Baboon CD74 antibody for Immunohistochemistry (Frozen Sections)

Recommended CD74 Antibody

Antigen
HLA-DR-gamma (CD74) Antibodies
  • DHLAG
  • HLADG
  • II
  • Ia-GAMMA
  • CLIP
  • Ii
  • INVG34
  • Iclp-1
  • iclp1
  • wu:fb11f09
  • wu:fb12a01
  • wu:fb13d06
  • wu:fk94e07
  • CD74 molecule
  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • CD74 molecule, major histocompatibility complex, class II invariant chain a
  • CD74
  • Cd74
  • cd74a
Reactivity
Baboon, Human, Mouse (Murine)
535
121
31
29
Host
Mouse
453
105
10
2
Clonality
Monoclonal
Conjugate
This CD74 antibody is un-conjugated
36
32
25
20
19
16
14
9
9
9
9
9
9
9
9
9
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
348
340
234
136
99
96
64
63
60
58
16
13
10
2
2
2
2
2
1
1
Options

Available images

Catalog No. ABIN4295634
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
4 ABIN241561 FACS IHC IHC (fro) IHC (p) IP Mouse IgG1, kappa LN2 0
4 ABIN1724032 IHC (fro) FACS IHC (p) IP Mouse IgG1 kappa LN2 0
-9.04131 ABIN4295642 CyTOF ELISA FACS ICC IF IHC (fro) IP WB Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295650 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 680 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295651 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 488 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295656 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 550 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295654 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB PerCP Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295657 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 350 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295653 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 755 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295643 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 405 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295644 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 488 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295645 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 647 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295646 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Alexa Fluor 700 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295648 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Biotin Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295649 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 650 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295658 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB DyLight 405 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN4295652 ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB HRP Mouse IgG1 kappa LN-2 0
-12.04131 ABIN5947520 FACS ICC IF IHC IHC (fro) IHC (p) Janelia Fluor® 549 Mouse IgG1 kappa LN-2 0
-12.04131 ABIN5947521 FACS ICC IF IHC IHC (fro) IHC (p) Janelia Fluor® 646 Mouse IgG1 kappa LN-2 0

General

Antigen HLA-DR-gamma (CD74) Antibodies
Reactivity Baboon, Human, Mouse (Murine)
(535), (121), (31), (29)
Host Mouse
(453), (105), (10), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD74 antibody is un-conjugated
(36), (32), (25), (20), (19), (16), (14), (9), (9), (9), (9), (9), (9), (9), (9), (9), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(348), (340), (234), (136), (99), (96), (64), (63), (60), (58), (16), (13), (10), (2), (2), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Supplier

Product Details anti-CD74 Antibody

Target Details CD74 Application Details Handling References for anti-CD74 antibody (ABIN4295634) Images
Specificity It recognizes a protein of ~35 kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+). This antibody can be used for the identification of B cell lymphoma and leukemias. It also stains activated neoplastic cells in T cell lymphomas and Sternberg-reed cells.
No Cross-Reactivity Rat (Rattus)
Purification Protein G purified
Immunogen SU-DHL-4 lymphoma cells were used as the immunogen for the CD74 antibody
Clone LN-2
Isotype IgG1 kappa
Plasmids, Primers & others

Target Details CD74

Product Details anti-CD74 Antibody Application Details Handling References for anti-CD74 antibody (ABIN4295634) Images back to top
Antigen
Alternative Name CD74 (CD74 Antibody Abstract)
Background Gene Symbol: CD74
Molecular Weight Theoretical MW: 37 kDa
Gene ID 972
UniProt P04233
Pathways Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints

Application Details

Product Details anti-CD74 Antibody Target Details CD74 Handling References for anti-CD74 antibody (ABIN4295634) Images back to top
Application Notes Western Blot 0.5-1 μg/mL, Flow Cytometry 0.5-1 μg/million cells, ELISA 1-5 μg/mL for coating, Immunohistochemistry 0.5-1 μg/mL, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunoprecipitation 1-2 μg/500 μg protein lysate, Immunohistochemistry-Paraffin 0.5-1 μg/mL, Immunohistochemistry-Frozen 0.5-1 μg/mLHuman Chromosome Location: 5q33.1 Use in Western Blot has been reported in literature. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-CD74 Antibody Target Details CD74 Application Details References for anti-CD74 antibody (ABIN4295634) Images back to top
Format Liquid
Buffer PBS with 0.05 % BSA.
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C.

References for anti-CD74 antibody (ABIN4295634)

Product Details anti-CD74 Antibody Target Details CD74 Application Details Handling Images back to top
Product cited in:

Zheng, Yang, Rong, Yuan, Ma, Wang, Shen, Cui: "CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer." in: World journal of gastroenterology : WJG, Vol. 18, Issue 18, pp. 2253-61, 2012

Images

Product Details anti-CD74 Antibody Target Details CD74 Application Details Handling References for anti-CD74 antibody (ABIN4295634) back to top
Supplier Images
Immunohistochemistry (Frozen Sections) (IHC (fro)) image for anti-HLA-DR-gamma (CD74) antibody (ABIN4295634) Immunohistochemistry-Frozen: CD74 Antibody (LN-2) [NBP2-29465] - Analysis using the A...