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anti-Human Dopamine d2 Receptor Antibodies:
anti-Mouse (Murine) Dopamine d2 Receptor Antibodies:
anti-Rat (Rattus) Dopamine d2 Receptor Antibodies:
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Human Polyclonal Dopamine d2 Receptor Primary Antibody for IF (p), IHC (p) - ABIN730858
Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells. in Acta pharmacologica Sinica 2014
Show all 6 Pubmed References
Human Polyclonal Dopamine d2 Receptor Primary Antibody for IHC (p) - ABIN4305945
Srirajaskanthan, Watkins, Marelli, Khan, Caplin: Expression of somatostatin and dopamine 2 receptors in neuroendocrine tumours and the potential role for new biotherapies. in Neuroendocrinology 2009
Show all 2 Pubmed References
Human Monoclonal Dopamine d2 Receptor Primary Antibody for ELISA, WB - ABIN515070
Akimoto, Furuse: SCH23390, a dopamine D1 receptor antagonist, suppressed scratching behavior induced by compound 48/80 in mice. in European journal of pharmacology 2011
Bat Polyclonal Dopamine d2 Receptor Primary Antibody for IHC (p) - ABIN4305946
Saveanu, Sebag, Guillet, Archange, Essamet, Barlier, Palazzo, Taïeb: Targeting dopamine receptors subtype 2 (D2DR) in pheochromocytomas: head-to-head comparison between in vitro and in vivo findings. in The Journal of clinical endocrinology and metabolism 2013
Human Polyclonal Dopamine d2 Receptor Primary Antibody for IHC, ELISA - ABIN1584371
Sakano, Choi, Kataoka, Shiraki, Uesugi, Kume, Kume: Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass. in Stem cell reports 2017
childhood urbanicity and variation in dopamine genes COMT (show COMT Antibodies), DRD1 (show DRD1 Antibodies) and DRD2 alters adult prefrontal function as measured by fMRI
analysis of molecular dynamics simulations with a cumulative length of ~77 mus of D2R and D3R wild-type and their E2.65A mutants bound to SB269652
In schizophrenia patients, presence of DRD2 Taq 1 D2D2 and 5-HT2A C516T CT genotypes in patients were more likely to be associated with non-response to risperidone.
These results led us to hypothesize the existence of functional D2-sigma1R (show SIGMAR1 Antibodies) complexes on the rat striatal DA and glutamate (show GRIN1 Antibodies) nerve terminals and functional D2-sigma1R (show SIGMAR1 Antibodies)-DA transporter (show SLC6A3 Antibodies) complexes on the striatal DA terminals.
The glioma-initiating cells self-renewal function regulated by PRRX1 (show PRRX1 Antibodies) is mediated by dopamine D2 receptor (DRD2). PRRX1 (show PRRX1 Antibodies) directly binds to the DRD2 promoter and transactivates its expression in glioma-initiating cells.
ONC201 is a selective DRD2 antagonist that is well tolerated, achieves micromolar plasma concentrations, and is biologically active in advanced cancer patients when orally administered at 625 mg every 3 weeks
DRD2 variation is associated with fiber tract integrity between basal ganglia and frontal cortices.
The G allele of rs4654327 (OPRD1 (show OPRD1 Antibodies)), DRD2 haplotype block CCGCCGTT (rs6277-rs1076560-rs2283265-rs2734833-rs2075652-rs1079596-rs4436578-rs11214607), and OPRD1 (show OPRD1 Antibodies) haplotypes TACG (rs6669447-rs2236857-rs508448-rs4654327), CG (rs508448-rs4654327), and TG (rs6669447-rs4654327) were significantly associated with heroin dependence phenotype.
The constructed models using 38 D2R ligands (in the training set) were validated with 15 additional test set compounds. The resulting model correctly predicted the pIC50 values of an additional test set compounds as true unknowns
case-control study by genotyping 7 SNPs of SLC6A2 (show SLC6A2 Antibodies), SLC6A3 (show SLC6A3 Antibodies) and DRD2 in 1034 schizophrenia patients and 1034 controls. No significant difference in the allelic or genotypic frequency was detected between cases and controls
Studied a novel Dopamine Receptor 2 (DRD2) G/A SNP for resistance to fescue toxicosis.
boosting dopamine signaling in the striatum by acute cocaine administration reveals that absence of D2L, but not of D2S, strongly impairs the motor and cellular response to the drug, in a manner similar to the ablation of both isoforms. These results suggest that when the dopamine system is challenged, D2L signaling is required for the control of striatal circuits regulating motor activity.
This study explored the spatial distribution of D2 medium-sized spiny neurons across the rostral-caudal (show CAD Antibodies) axis of the striatum using D2-eGFP double transgenic mice.
Pre- and postsynaptic colocalization of kappa opioid receptor (show OPRK1 Antibodies) and D2R supports a role for kappa opioid receptor (show OPRK1 Antibodies) potentiating both the D2R inhibitory autoreceptor function and the inhibitory action of D2R on efferent medium spiny neurons. Kappa opioid receptor (show OPRK1 Antibodies) co-activation accelerates D2R sensitization by contributing to decrease dopamine release in the nucleus accumbens.
Study shows that social isolation to a series of schizophrenia-related deficits and that potential interactions among histidine triad nucleotide binding protein 1 (show HINT1 Antibodies), NMDA receptor 1 (show GRIN1 Antibodies), and dopamine receptor 2 may underlie the behavioral deficits induced by social isolation.
These results are in support of intrastriatal connections of D2R(+)-MSNs (iMSNs) with dMSNs and indicate that D2R signaling in MSNs is critical for the function of intrastriatal circuits.
Dopamine D2L isoform receptors and nucleus accumbens D2 receptor medium spiny neurons act to suppress the influence of previously correct behavioral strategies allowing transfer of behavioral control to new strategies.
Localization of the dopamine receptors of types 1 and 2 on the bodies of POMC (show POMC Antibodies)-expressing neurons of the arcuate nucleus of the hypothalamus in mice and rats.
D2 receptor (D2R) +/+ enriched environment (EE) mice lived nearly 16% longer than their deprived environment (DE) counterparts.
Further analysis revealed that the adenosine agonist 5'-N-ethylcarboxamidoadenosine, a previously identified promoter of b cell proliferation, acted with DPD (show DPYD Antibodies) to increase the number of b cells. In humans, dopamine also modulates b cell mass through DRD2 and exerts an inhibitory effect on adenosine signaling
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
Mapped associations occur between changes in D2 and D3 dopamine receptor (show DRD3 Antibodies) occupancy and brain hemodynamics
These data provide evidence for a predisposition to self-administer cocaine based on dopamine D2 receptor availability, and demonstrate that the brain dopamine system responds rapidly following cocaine exposure.
The amount of dopamine d1 receptor (show DRD1 Antibodies), dopamine D2 receptor, and follicle stimulating hormone receptor (show FSHR Antibodies) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.
The pig DRD2 gene was cloned, investigated its distribution in tissues and polymorphisms were identified.
The increase in NOS (show NOS Antibodies) protein seen in both the endothelium and vascular smooth muscle in response to cerebral vasospasm is enhanced by dopamine in a D(2)R-dependent mechanism.
Damb receptor uniquely activates Gq to mobilize Ca(2 (show CA2 Antibodies)+) signaling with greater efficiency and dopamine sensitivity
Findings suggest a role for dopamine D1-like receptor (show DRD1 Antibodies) Dop1R2 in the repression of genes that coordinate metamorphosis.
Results suggest that the activation state of DAMB protein contributes to oxidative stress susceptibility in Drosophila and lead to a proposed model for paraquat neurotoxicity.
Dopamine D2 receptor play role in memory consolidation.
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia\; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
D(2) dopamine receptor
, dopamine D2 receptor
, dopamine receptor D2 isoform
, seven transmembrane helix receptor
, D2 dopamine receptor
, Dopamine D2 receptor
, dopamine receptor D2b
, dopamine D2 receptor 2
, D2 receptor
, dopamine receptor 2
, D(2) dopamine receptor A
, D2R 1
, dopamine receptor D2
, dopamine receptor 2 protein
, D[]-like receptor
, dopamine receptor in mushroom bodies
, dopamine-2 receptor