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anti-Human Dopamine d2 Receptor Antibodies:
anti-Mouse (Murine) Dopamine d2 Receptor Antibodies:
anti-Rat (Rattus) Dopamine d2 Receptor Antibodies:
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Human Polyclonal Dopamine d2 Receptor Primary Antibody for IF (p), IHC (p) - ABIN730858
Xu, Wang, Chen, Chen, Li, Shao, Li, Lu, Zhou: Dopamine D1 receptor activation induces dehydroepiandrosterone sulfotransferase (SULT2A1) in HepG2 cells. in Acta pharmacologica Sinica 2014
Show all 6 Pubmed References
Human Polyclonal Dopamine d2 Receptor Primary Antibody for IHC (p) - ABIN4305945
Srirajaskanthan, Watkins, Marelli, Khan, Caplin: Expression of somatostatin and dopamine 2 receptors in neuroendocrine tumours and the potential role for new biotherapies. in Neuroendocrinology 2009
Show all 2 Pubmed References
Human Monoclonal Dopamine d2 Receptor Primary Antibody for ELISA, WB - ABIN515070
Akimoto, Furuse: SCH23390, a dopamine D1 receptor antagonist, suppressed scratching behavior induced by compound 48/80 in mice. in European journal of pharmacology 2011
Bat Polyclonal Dopamine d2 Receptor Primary Antibody for IHC (p) - ABIN4305946
Saveanu, Sebag, Guillet, Archange, Essamet, Barlier, Palazzo, Taïeb: Targeting dopamine receptors subtype 2 (D2DR) in pheochromocytomas: head-to-head comparison between in vitro and in vivo findings. in The Journal of clinical endocrinology and metabolism 2013
Human Polyclonal Dopamine d2 Receptor Primary Antibody for IHC, ELISA - ABIN1584371
Sakano, Choi, Kataoka, Shiraki, Uesugi, Kume, Kume: Dopamine D2 Receptor-Mediated Regulation of Pancreatic β Cell Mass. in Stem cell reports 2017
ONC201 is a selective DRD2 antagonist that is well tolerated, achieves micromolar plasma concentrations, and is biologically active in advanced cancer patients when orally administered at 625 mg every 3 weeks
DRD2 variation is associated with fiber tract integrity between basal ganglia and frontal cortices.
The G allele of rs4654327 (OPRD1 (show OPRD1 Antibodies)), DRD2 haplotype block CCGCCGTT (rs6277-rs1076560-rs2283265-rs2734833-rs2075652-rs1079596-rs4436578-rs11214607), and OPRD1 (show OPRD1 Antibodies) haplotypes TACG (rs6669447-rs2236857-rs508448-rs4654327), CG (rs508448-rs4654327), and TG (rs6669447-rs4654327) were significantly associated with heroin dependence phenotype.
The constructed models using 38 D2R ligands (in the training set) were validated with 15 additional test set compounds. The resulting model correctly predicted the pIC50 values of an additional test set compounds as true unknowns
case-control study by genotyping 7 SNPs of SLC6A2 (show SLC6A2 Antibodies), SLC6A3 (show SLC6A3 Antibodies) and DRD2 in 1034 schizophrenia patients and 1034 controls. No significant difference in the allelic or genotypic frequency was detected between cases and controls
typical age-related dopamine D2 receptor loss, assessed with PET [18F]fallypride, was significantly reduced in physically active adults compared to less active adults
No correlation was found between DRD2 polymorphisms and CAB (show CA1 Antibodies) responsiveness in patients with prolactinoma. More data are necessary in order to assess the influence of DRD2 genotyping on DA treatment response.
DRD2 C947T (rs6277) may be associated with better performance on select cognitive domains independent of ANKK1 (show ANKK1 Antibodies) following Traumatic brain injury.
The major allele A of rs2511521 located in DRD2 and the minor allele T of rs625413 located in TIRAP (show TIRAP Antibodies) are significantly associated with increased risk of food addiction in overweight/obese subjects with low/zero food addiction symptoms.
finding substantiates the conclusion that the detected community represents a more connected and informative cluster of genes for the DRD2 community, and therefore better elucidates the behavior of this module of strongly related DRD2 genes
Studied a novel Dopamine Receptor 2 (DRD2) G/A SNP for resistance to fescue toxicosis.
Pre- and postsynaptic colocalization of kappa opioid receptor (show OPRK1 Antibodies) and D2R supports a role for kappa opioid receptor (show OPRK1 Antibodies) potentiating both the D2R inhibitory autoreceptor function and the inhibitory action of D2R on efferent medium spiny neurons. Kappa opioid receptor (show OPRK1 Antibodies) co-activation accelerates D2R sensitization by contributing to decrease dopamine release in the nucleus accumbens.
Study shows that social isolation to a series of schizophrenia-related deficits and that potential interactions among histidine triad nucleotide binding protein 1 (show HINT1 Antibodies), NMDA receptor 1 (show GRIN1 Antibodies), and dopamine receptor 2 may underlie the behavioral deficits induced by social isolation.
These results are in support of intrastriatal connections of D2R(+)-MSNs (iMSNs) with dMSNs and indicate that D2R signaling in MSNs is critical for the function of intrastriatal circuits.
Dopamine D2L isoform receptors and nucleus accumbens D2 receptor medium spiny neurons act to suppress the influence of previously correct behavioral strategies allowing transfer of behavioral control to new strategies.
Localization of the dopamine receptors of types 1 and 2 on the bodies of POMC (show POMC Antibodies)-expressing neurons of the arcuate nucleus of the hypothalamus in mice and rats.
D2 receptor (D2R) +/+ enriched environment (EE) mice lived nearly 16% longer than their deprived environment (DE) counterparts.
Further analysis revealed that the adenosine agonist 5'-N-ethylcarboxamidoadenosine, a previously identified promoter of b cell proliferation, acted with DPD (show DPYD Antibodies) to increase the number of b cells. In humans, dopamine also modulates b cell mass through DRD2 and exerts an inhibitory effect on adenosine signaling
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
Results show that deleted in colorectal cancer (show DCC Antibodies) receptors contribute to the dynamic refinement of dopamine D1 and D2 receptor expression in striatal regions across adolescence. The age-dependent expression of dopamine receptor in C57BL6 mice shows marked differences from previous characterizations in rats.
The expression of Klf15 is increased during neuropathic pain. TNF-alpha regulates the expression of Klf15. KLF15 regulates the expression of dopamine D2 receptor. KLF15 regulates neuropathic pain in mouse models.
Mapped associations occur between changes in D2 and D3 dopamine receptor (show DRD3 Antibodies) occupancy and brain hemodynamics
These data provide evidence for a predisposition to self-administer cocaine based on dopamine D2 receptor availability, and demonstrate that the brain dopamine system responds rapidly following cocaine exposure.
The amount of dopamine d1 receptor (show DRD1 Antibodies), dopamine D2 receptor, and follicle stimulating hormone receptor (show FSHR Antibodies) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.
The pig DRD2 gene was cloned, investigated its distribution in tissues and polymorphisms were identified.
The increase in NOS (show NOS Antibodies) protein seen in both the endothelium and vascular smooth muscle in response to cerebral vasospasm is enhanced by dopamine in a D(2)R-dependent mechanism.
Findings suggest a role for dopamine D1-like receptor (show DRD1 Antibodies) Dop1R2 in the repression of genes that coordinate metamorphosis.
Results suggest that the activation state of DAMB protein contributes to oxidative stress susceptibility in Drosophila and lead to a proposed model for paraquat neurotoxicity.
Dopamine D2 receptor play role in memory consolidation.
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia\; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
D(2) dopamine receptor
, dopamine D2 receptor
, dopamine receptor D2 isoform
, seven transmembrane helix receptor
, D2 dopamine receptor
, Dopamine D2 receptor
, dopamine receptor D2b
, dopamine D2 receptor 2
, D2 receptor
, dopamine receptor 2
, D(2) dopamine receptor A
, D2R 1
, dopamine receptor D2
, dopamine receptor 2 protein
, D[]-like receptor
, dopamine receptor in mushroom bodies
, dopamine-2 receptor