Protein Summary

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with RAD9A

• RAD9 checkpoint clamp component A (RAD9A) antibody
• RAD9 checkpoint clamp component A (Rad9a) antibody
• RAD9 checkpoint clamp component A (rad9a) antibody
• RAD9 checkpoint clamp component B (rad9b) antibody
• RAD9 checkpoint clamp component A L homeolog (rad9a.L) antibody

• MGC89062 antibody
• rad9 antibody
• rad9a antibody
• XRad9 antibody

Protein level used designations for RAD9A

DNA repair exonuclease rad9 homolog A , cell cycle checkpoint control protein RAD9A , hRAD9 , RAD9 homolog A (S. pombe) , cell cycle checkpoint control protein RAD9A-like , Rad9-like protein , mRAD9 , RAD9 homolog A , rCG47324-like , PCNA-like DNA checkpoint protein Rad9 , RAD9 checkpoint clamp component A L homeolog