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Mouse (Murine) Polyclonal OPRD1 Primary Antibody for ICC, IF - ABIN250449
Ko, Arvidsson, Williams, Law, Elde, Loh: Visualization of time-dependent redistribution of delta-opioid receptors in neuronal cells during prolonged agonist exposure. in Brain research. Molecular brain research 1999
Show all 3 Pubmed References
Human Polyclonal OPRD1 Primary Antibody for WB - ABIN2690091
Wu, Li, Wu: The effect of chronic intermittent hypoxia on respiratory sensitivity to morphine in rats. in Sleep & breathing = Schlaf & Atmung 2017
OPRD1 gene variants and their haplotypes can play important roles in susceptibility to opioid dependence.
Homozygotes AA at rs6265 (BDNF (show BDNF Antibodies)), TT at rs16917234 (BDNF (show BDNF Antibodies)), and CC at rs508448 (OPRD1) also appeared as risk factors for the endophenotype earlier age of onset for heroin use.
Functional activity of Dynorphin 1-17 and fragments (1-6, 1-7 and 1-9) were screened over a range of concentrations against forskolin stimulated human embryonic kidney 293 (HEK (show EPHA3 Antibodies)) cells stably transfected with one of KOP (show SPINT2 Antibodies), MOP (show NLN Antibodies) or DOP (show COPB2 Antibodies)
A polymorphism in OPRD1 appears to be associated with both cocaine dependence and cocaine use during treatment in African-Americans. Follow-up studies to confirm the effect on cocaine use are warranted.
OPRD1 promoter hypermethylation is associated with the risk of AD
After inhibition of the PKC/ERK signalling pathway, the effects of DOR on breast cancer were significantly attenuated in vivo and in vitro. In summary, DOR is highly expressed in breast cancer and is closely related to its progression. These results suggest that DOR may serve as a potential biomarker for the early diagnosis of breast cancer and may be a viable molecular target for therapeutic intervention.
The study successfully developed a population PKPD model for oxycodone across three experimental pain types and investigated the association between 18 SNPs across all three opioid receptor genes (OPRM1 (show OPRM1 Antibodies), OPRK1 (show OPRK1 Antibodies), OPRD1) and analgesic response from oxycodone. None of the selected polymorphisms were significantly associated with analgesic response of oxycodone.
the expression of DOR was upregulated in the drugresistant human hepatocellular carcinoma cells.
OPRD-mediated activation of ERK1/2 is via ligand-specific transactivation of EGFR (show EGFR Antibodies).
findings suggest that SNPs in opioid receptors and the PNOC (show PNOC Antibodies) genes are associated with NAS (show SCN9A Antibodies) severity.
DOR regulates the reinforcing effects and motivation for palatable food through neuroplastic changes in specific brain reward areas.
it showed that the antinociception of ghrelin (show GHRL Antibodies) was correlated with the GHS-R1alpha and d-opioid receptors. Finally, the antinociception induced by deltorphin II wasn't blocked by the co-injection (i.c.v.) of [D-Lys (show LYZ Antibodies)(3)]-GHRP (show GHSR Antibodies)-6, indicating that the GHS-R1a isn't on the backward position of delta opioid receptor.
Delta opioid receptor (DOR) expressed in the forebrain mediate the described locomotor effect of SNC80 (DOR agonist) and inhibit D1-stimulated hyperactivity. Data also reveals an anxiogenic role for this particular DOR subpopulation.
Anti-nociception mediated by a KOR agonist is blocked by a DOR agonist
we have demonstrated for the first time that DOR receptor activation induces astrocytic expression of EAAT1 (show SLC1A3 Antibodies) and EAAT2 (show SLC1A2 Antibodies)
The results of this study indicated that delta-opioid receptor have a differential role in cue-induced reinstatement of cocaine-seeking behavior.
findings show that, during prolonged heroin abstinence, delta opioid receptors regulate hedonic homeostasis, while mu opioid receptor (show OPRM1 Antibodies) signaling in serotonergic pathways and kappa opioid receptors together control social behaviors
a role for differential modulation of opioid receptor signaling by post-endocytic processing of peptide agonists by ECE2 (show ECE2 Antibodies).
SSTR4 and delta-Opioid receptor (dOR) exist in a heteromeric complex and function in synergistic manner.
Our study suggests that MOR(mu opioid receptors) and DOR(delta opioid receptors are involved in the interactions between cocaine and both deltorphins analogs
This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance.
, delta opioid receptor 1
, delta-type opioid receptor
, opioid receptor A
, delta 1 opioid receptor
, Delta-type opioid receptor
, delta opioid receptor