OPRD1 antibody (C-Term)

Catalog No. ABIN6257142

Product Details anti-OPRD1 Antibody

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPRD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: OPRD1 Antibody detects endogenous levels of total OPRD1.

Predicted Reactivity: Bovine,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human OPRD1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for OPRD1

Target: OPRD1 (Opioid Receptor, delta 1 (OPRD1))

Alternative Name: OPRD1 (OPRD1 Products)

Synonyms: OPRD antibody, DOR-1 antibody, Nbor antibody, mDOR antibody, opioid receptor delta 1 antibody, opioid receptor, delta 1 antibody, OPRD1 antibody, Oprd1 antibody

Background:

Description: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Gene: OPRD1

Molecular Weight: 36 kDa

Gene ID: 4985

UniProt: P41143

Pathways: Protein targeting to Nucleus