SERPINA4 Protein (AA 21-427) (His tag)

Catalog No. ABIN1097508

Product Details

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Protein Type: Recombinant

Protein Characteristics: AA 21-427

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This SERPINA4 protein is labelled with His tag.

Purpose: Recombinant Human Serpin A4/Kallistatin (C-6His)

Sequence: QLHVEHDGES CSNSSHQQIL ETGEGSPSLK IAPANADFAF RFYYLIASET PGKNIFFSPL SISAAYAMLS LGACSHSRSQ ILEGLGFNLT ELSESDVHRG FQHLLHTLNL PGHGLETRVG SALFLSHNLK FLAKFLNDTM AVYEAKLFHT NFYDTVGTIQ LINDHVKKET RGKIVDLVSE LKKDVLMVLV NYIYFKALWE KPFISSRTTP KDFYVDENTT VRVPMMLQDQ EHHWYLHDRY LPCSVLRMDY KGDATVFFIL PNQGKMREIE EVLTPEMLMR WNNLLRKRNF YKKLELHLPK FSISGSYVLD QILPRLGFTD LFSKWADLSG ITKQQKLEAS KSFHKATLDV DEAGTEAAAA TSFAIKFFSA QTNRHILRFN RPFLVVIFST STQSVLFLGK VVDPTKPHHH HHH

Characteristics: Recombinant Human Serpin A4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln21-Pro427) of Human SERPINA4 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM TrisHCl, 150 mM NaCl, 10 mM NaCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Alternative Name: Serpin-A4 (SERPINA4 Products)

Synonyms: KLKR Protein, Klk6 Protein, hK1 Protein, KAL Protein, KLST Protein, KST Protein, PI-4 Protein, PI4 Protein, kallistatin Protein, SERPINA4 Protein, DKFZp469E1737 Protein, KALps Protein, Klst Protein, kallikrein 1 Protein, serpin family A member 4 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 Protein, serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 Protein, KLK1 Protein, SERPINA4 Protein, Serpina4 Protein, SPIA4 Protein, Serpina4-ps1 Protein

Sub Type: Fusionprotein

Background: Serpin Peptidase Inhibitor, Clade A (alpha-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition, Serpin A4 has anti-inflammatory effect. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.
Alternative Names: Kallistatin, Kallikrein Inhibitor, Peptidase Inhibitor 4, PI-4, Serpin A4, SERPINA4, KST, PI4

Molecular Weight: 47.1 kDa

UniProt: P29622