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SERPINA4 Protein (His tag)

Recombinant SERPINA4 protein expressed in Human Cells.
Catalog No. ABIN7319016

Quick Overview for SERPINA4 Protein (His tag) (ABIN7319016)

Target

See all SERPINA4 Proteins
SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Protein Type

Recombinant

Origin

Human

Source

  • 1
  • 1
  • 1
  • 1
Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This SERPINA4 protein is labelled with His tag.

    Purpose

    Recombinant Human SerpinA4/SERPINA4 Protein (His Tag)

    Sequence

    Gln21-Pro427

    Characteristics

    Recombinant Human Serine Protease Inhibitor-clade A4 is produced by our Mammalian expression system and the target gene encoding Gln21-Pro427 is expressed with a 6His tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 50 mM TrisHCl, 150 mM NaCl, 10 mM NaCl, pH 8.0.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

    Alternative Name

    SerpinA4/SERPINA4

    Background

    Background: Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition, Serpin A4 has anti-inflammatory effect. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.

    Synonym: Kallistatin, Kallikrein Inhibitor, Peptidase Inhibitor 4, PI-4, Serpin A4, SERPINA4, KST, PI4

    Molecular Weight

    47.1 kDa

    UniProt

    P29622
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