RAP2B, Member of RAS Oncogene Family (RAP2B) protein (His tag)

Details for Product No. ABIN1098540
Protein Name
Origin
Human
5
1
1
Source
Escherichia coli (E. coli)
3
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This RAP2B protein is labelled with His tag.
Application
SDS-PAGE (SDS)
Options
Purification purified by chromatography
Purity > 95 % by SDS - PAGE
Protein Name
Background Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molecular Weight 22.9kDa (206aa) confirmed by MALDI-TOF
NCBI Accession NP_002877
Comment

Synonyms: Ras-related protein Rap-2b, RAP2B, member of RAS oncogene family

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/ml (determined by Bradford assay)
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
Storage 4 °C
Storage Comment Avoid repeated freezing and thawing cycles.
Supplier Images
Image no. 1 for RAP2B, Member of RAS Oncogene Family (RAP2B) protein (His tag) (ABIN1098540) RAP2B, Member of RAS Oncogene Family (RAP2B) protein (His tag)