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RAP2B Protein (His tag)

RAP2B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN1098540
  • Target See all RAP2B Proteins
    RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RAP2B protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product RAP2B Protein
  • Comment

    Synonyms: Ras-related protein Rap-2b, RAP2B, member of RAS oncogene family

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    RAP2B (RAP2B, Member of RAS Oncogene Family (RAP2B))
    Alternative Name
    RAP2B (RAP2B Products)
    Synonyms
    Rap2b Protein, wu:fi34c06 Protein, zgc:55550 Protein, RAP2B Protein, LOC100223676 Protein, 4021402C18Rik Protein, AA408554 Protein, RAP2B, member of RAS oncogene family S homeolog Protein, RAP2B, member of RAS oncogene family Protein, RAS-like, family 10, member A Protein, GTP-binding protein Rhes pseudogene Protein, rap2b.S Protein, rap2b Protein, RASL10A Protein, RAP2B Protein, LOC100223676 Protein, Rap2b Protein
    Background
    Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. Unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    22.9kDa (206aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_002877
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