MBL2 Protein (AA 108-248) (His tag)
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- Target See all MBL2 Proteins
- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 108-248
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MBL2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product MBL2 Protein
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- Comment
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Synonyms: Mannose-binding protein C, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M Nacl
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Target
- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
- Alternative Name
- MBL2 (MBL2 Products)
- Background
- Mannose-binding protein C, also known as MBL2, is a member of the collectin family of patternrecognition molecules. MBL2 is a secreted glycoprotein that is synthesized as a 248 amino acid precursor. The Protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. Recombinant human MBL2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 18 kDa (164aa)
- NCBI Accession
- NP_000233
- UniProt
- P11226
- Pathways
- Complement System, Positive Regulation of Immune Effector Process
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