IL1F9 Protein (DYKDDDDK Tag)
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- Target See all IL1F9 Proteins
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This IL1F9 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Purpose
- IL-36gamma (aa 13-164) (mouse) (rec.) (FLAG)
- Cross-Reactivity
- Mouse
- Characteristics
- Mouse IL-36gamma (aa Gly13-Ser164) is fused at the C-terminus to a FLAG®-tag.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
- Biological Activity Comment
- Induces secretion of IL-6 in BMDCs.
- Top Product
- Discover our top product IL1F9 Protein
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Interleukin 1 Family Member 9 (IL1F9) (AA 13-164) protein (His tag)
IL1F9 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interleukin 1 Family Member 9 (IL1F9) (AA 18-169) protein (His tag)IL1F9 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- 0.1 mg/mL
- Buffer
- Contains PBS.
- Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
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- Target
- IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
- Alternative Name
- IL-36gamma (IL1F9 Products)
- Background
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Interleukin-36gamma, Interleukin-1 Family Member 9, IL-1F9
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
- Molecular Weight
- ~17kDa
- UniProt
- Q8R460
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