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IL1F9 Protein (DYKDDDDK Tag)

IL1F9 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS Active
Catalog No. ABIN1344114
  • Target See all IL1F9 Proteins
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 4
    • 1
    Mouse
    Source
    • 15
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IL1F9 protein is labelled with DYKDDDDK Tag.
    Application
    SDS-PAGE (SDS)
    Purpose
    IL-36gamma (aa 13-164) (mouse) (rec.) (FLAG)
    Cross-Reactivity
    Mouse
    Characteristics
    Mouse IL-36gamma (aa Gly13-Ser164) is fused at the C-terminus to a FLAG®-tag.
    Purity
    >95 % (SDS-PAGE)
    Endotoxin Level
    <0.01EU/μg purified protein (LAL test).
    Biological Activity Comment
    Induces secretion of IL-6 in BMDCs.
    Top Product
    Discover our top product IL1F9 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    0.1 mg/mL
    Buffer
    Contains PBS.
    Handling Advice
    After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
    Storage
    4 °C,-20 °C
    Storage Comment

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

    Expiry Date
    6 months
  • Target
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    Alternative Name
    IL-36gamma (IL1F9 Products)
    Background

    Interleukin-36gamma, Interleukin-1 Family Member 9, IL-1F9

    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

    Molecular Weight
    ~17kDa
    UniProt
    Q8R460
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