Hemagglutinin Protein (HA) (AA 19-338, AA 341-523) (Fc Tag)

Catalog No. ABIN2181208

Product Details

Target: Hemagglutinin (HA)

Protein Type: Recombinant

Protein Characteristics: AA 19-338, AA 341-523

Origin: Influenza Virus

Virus Strain: A/Shanghai/2/2013

Source: HEK-293 Cells

Purification tag / Conjugate: This Hemagglutinin protein is labelled with Fc Tag.

Sequence: AA 19-338,AA 341-523

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 84.5 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: >95 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Target Details

Target: Hemagglutinin (HA)

Abstract: HA Products

Target Type: Influenza Protein

Background: Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.

Molecular Weight: 82.5 kDa

Gene ID: 18, 17