IFNAR2 Protein (AA 27-243) (His tag)
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- Target See all IFNAR2 Proteins
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-243
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFNAR2 protein is labelled with His tag.
- Sequence
- AA 27-243
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.6 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IFNAR2 Protein
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Interferon alpha/beta Receptor 2 (IFNAR2) (AA 144-243) protein (GST tag)
IFNAR2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 264-513) protein (His tag)Crystallography grade IFNAR2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 265-515) protein (His tag)Crystallography grade IFNAR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 27-243) protein (His tag)Crystallography grade IFNAR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 22-242) protein (His tag)Crystallography grade IFNAR2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 27-515) protein (rho-1D4 tag)Crystallography grade IFNAR2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interferon alpha/beta Receptor 2 (IFNAR2) (AA 22-513) protein (rho-1D4 tag)Crystallography grade IFNAR2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
- Alternative Name
- IFNAR2 (IFNAR2 Products)
- Synonyms
- AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein
- Background
- Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.
- Molecular Weight
- 25.8 kDa
- NCBI Accession
- NP_997467
- Pathways
- JAK-STAT Signaling, Hepatitis C
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