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IL21 Receptor Protein (Interleukin 21 Receptor) (AA 20-236) (His tag)

IL21R Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. Active
Catalog No. ABIN2181372
$318.46
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  • Target See all IL21 Receptor (IL21R) Proteins
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 20-236
    Origin
    • 12
    • 6
    • 1
    • 1
    Human
    Source
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL21 Receptor protein is labelled with His tag.
    Sequence
    AA 20-236
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.8 kDa. The protein migrates as 42-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >92 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    Alternative Name
    IL-21 R (IL21R Products)
    Synonyms
    IL21R, il-21ra.a, CD360, NILR, interleukin 21 receptor, interleukin 21 receptor, tandem duplicate 1, IL21R, il21r.1, Il21r
    Background
    Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
    Molecular Weight
    26.1 kDa
    Pathways
    JAK-STAT Signaling
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