SIGLEC6 Protein (Fc Tag)

Catalog No. ABIN2566933

Product Details

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SIGLEC6 protein is labelled with Fc Tag.

Application: Western Blotting (WB)

Characteristics:

Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn).

Fusion tag: C-Fc Tag

Purity: >92 % as determined by SDS-PAGE.

Application Details

Application Notes: This recombinant protein can be used for WB. For research use only.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM tris, 100 mM glycine, pH 7.5

Storage: -80 °C,-20 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Target Details

Target: SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))

Alternative Name: SIGLEC6 (SIGLEC6 Products)

Synonyms: SIGLEC6 Protein, CD327 Protein, CD33L Protein, CD33L1 Protein, CD33L2 Protein, CDW327 Protein, OBBP1 Protein, sialic acid binding Ig like lectin 6 Protein, SIGLEC6 Protein

Background: Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Molecular Weight: 60.3 kDa

Gene ID: 946

UniProt: O43699