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SIGLEC6 Protein (Fc Tag)

SIGLEC6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7317395
  • Target See all SIGLEC6 Proteins
    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SIGLEC6 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human SIGLEC6/CD327 Protein (Fc Tag)
    Sequence
    Gln27-Val331
    Characteristics
    A DNA sequence encoding the human SIGLEC6 (O43699-3) (Gln27-Val331) was expressed with the Fc region of human IgG1 at the C-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product SIGLEC6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
    Alternative Name
    SIGLEC6/CD327 (SIGLEC6 Products)
    Synonyms
    SIGLEC6 Protein, CD327 Protein, CD33L Protein, CD33L1 Protein, CD33L2 Protein, CDW327 Protein, OBBP1 Protein, sialic acid binding Ig like lectin 6 Protein, SIGLEC6 Protein
    Background

    Background: SIGLEC6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC6 is a sialic acid recognizing protein expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. SIGLEC6 localizes in various compartments such as membrane fraction, extracellular region and so on. SIGLEC6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor.  Interestingly, expression of SIGLEC6 is further upregulated in pre-eclampsia, which appears to be a uniquely human disease.

    Synonym: CD327;CD33L;CD33L1;CD33L2;CDW327;OBBP1;SIGLEC6

    Molecular Weight
    60.7 kDa
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