CYLD Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all CYLD Proteins
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CYLD protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CYLD (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CYLD Protein
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Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-956) protein (His tag)
custom-made CYLD Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-226) protein (His-IF2DI Tag)CYLD Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 1-952) protein (His tag)custom-made CYLD Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)CYLD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CYLD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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-
: "CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density." in: PLoS ONE, Vol. 9, Issue 3, pp. e91312, (2014) (PubMed).
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: "CaMKII mediates recruitment and activation of the deubiquitinase CYLD at the postsynaptic density." in: PLoS ONE, Vol. 9, Issue 3, pp. e91312, (2014) (PubMed).
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- Target
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Alternative Name
- Cyld (CYLD Products)
- Background
- This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molecular Weight
- 106.9 kDa
- NCBI Accession
- NP_001035814
- Pathways
- Apoptosis, Activation of Innate immune Response
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