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CLCA2 Protein (Myc-DYKDDDDK Tag)

CLCA2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712858
  • Target See all CLCA2 Proteins
    CLCA2 (Chloride Channel Accessory 2 (CLCA2))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 4
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CLCA2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CLCA2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CLCA2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CLCA2 (Chloride Channel Accessory 2 (CLCA2))
    Alternative Name
    Clca2 (CLCA2 Products)
    Synonyms
    CACC Protein, CACC3 Protein, CLCRG2 Protein, CaCC-3 Protein, CLCA Protein, Clca4 Protein, rbCLCA Protein, 4732440A06 Protein, AI586120 Protein, Clca2 Protein, chloride channel accessory 2 Protein, calcium-activated chloride channel regulator 2 Protein, chloride channel calcium activated 2 Protein, chloride channel calcium activated 5 Protein, CLCA2 Protein, LOC100081268 Protein, Clca2 Protein, Clca5 Protein
    Background
    This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines.
    Molecular Weight
    100.6 kDa
    NCBI Accession
    NP_006527
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