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Heparanase (HPSE) protein (His tag) Protein

HPSE Origin: Human Source: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2722622
$302.50
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50 μg
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  • Protein Name
    Protein Type
    Recombinant
    Origin
    Human
    Source
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    His tag
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human Heparanase / HPSE (N-term HIS tag, transcript variant 1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    50 mM Tris,8M Urea, pH 8.0.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Protein Name
    Synonyms
    im:7144134, hpa, hpa1, hpr1, hpse1, hse1, HPSE, HPA, HPA1, HPR1, HPSE1, HSE1, Hpa, Hpr1, Hep, heparanase, HPSE, hpse, Hpse
    Background
    Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    61 kDa
    NCBI Accession
    NP_006656
    Pathways
    Glycosaminoglycan Metabolic Process
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