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WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

WWP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2735648
$971.30
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20 μg
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  • Target
    WWP2
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This WWP2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human WWP2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    WWP2
    Synonyms
    aip2, wwp2-like, id:ibd1121, wu:fo87e10, zgc:154036, AIP2, WWp2-like, 1300010O06Rik, AA690238, AW554328, WW domain containing E3 ubiquitin protein ligase 2, WWP2, wwp2, Wwp2
    Background
    This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.
    Molecular Weight
    50.9 kDa
    NCBI Accession
    NP_955456
    Pathways
    Negative Regulation of Transporter Activity
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