DLL1 Protein (AA 18-545) (Fc Tag)
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- Target See all DLL1 Proteins
- DLL1 (delta-Like 1 (DLL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 18-545
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Origin
- Human
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Source
- CHO Cells
- Purification tag / Conjugate
- This DLL1 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Purpose
- DLL1 (human):Fc (human) (rec.)
- Specificity
- Interacts with human Notch1 (as confirmed by flow cytometry).
- Cross-Reactivity
- Human
- Characteristics
- Human DLL1 extracellular domain (aa 18-545) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test).
- Biological Activity Comment
- Inhibits adipogenesis of 3T3L-1 cells. Induces the Notch target gene HES-1 when coated on a plate at 1μg/ml.
- Top Product
- Discover our top product DLL1 Protein
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delta-Like 1 (DLL1) (AA 18-540) protein (His tag)
DLL1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 (DLL1) protein (Fc Tag)DLL1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
delta-Like 1 (DLL1) (Active) protein (His tag)DLL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in distilled water.
- Concentration
- Lot specific
- Buffer
- Contains PBS.
- Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
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- Target
- DLL1 (delta-Like 1 (DLL1))
- Alternative Name
- DLL1 (DLL1 Products)
- Background
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Delta-like Protein 1, Delta1
DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
- Molecular Weight
- ~100kDa (SDS-PAGE)
- UniProt
- O00548
- Pathways
- Notch Signaling, Stem Cell Maintenance
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