Glypican 3 Protein (GPC3) (AA 25-557) (Fc Tag)
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- Target See all Glypican 3 (GPC3) Proteins
- Glypican 3 (GPC3)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 25-557
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glypican 3 protein is labelled with Fc Tag.
- Application
- Functional Studies (Func)
- Sequence
- AA 25-557
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 87.2 kDa. GP3-M5254 may be cleaved into secrete GPC3, short propeptide (aa ?-557) & Fc tag, long propeptide (aa 358-557 predicted) & Fc tag. The protein migrates as 100 kDa (secrete GPC3 & propeptide & Fc tag), 58 kDa (long propeptide & Fc tag), 40 kDa (short propeptide & Fc tag) and 35 kDa Human IgG1 Fc fragment on a SDS-PAGE gel under reducing (R) condition.
- Purity
- >90 % as determined by SDS-PAGE
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GPC3 Protein
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Glypican 3 (GPC3) (AA 25-559) protein (His tag)
GPC3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 25-559) protein (His tag)GPC3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) (AA 25-559) protein (His-Avi Tag,Biotin)GPC3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Glypican 3 (GPC3) protein (Fc Tag)GPC3 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Glypican 3 (GPC3) (AA 438-554) (Active) protein-VLPGPC3 Origin: Human Host: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (Fc Tag)GPC3 Origin: Cynomolgus Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (Fc Tag)GPC3 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE Func Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (His tag)GPC3 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Glypican 3 (GPC3) (AA 25-559) (Active) protein (His tag,AVI tag,Biotin)GPC3 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE. Active
Glypican 3 (GPC3) protein (His tag)GPC3 Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- Glypican 3 (GPC3)
- Alternative Name
- Glypican 3 (GPC3 Products)
- Background
- Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
- Molecular Weight
- 38.0 kDa and 49.1 kDa
- NCBI Accession
- NP_057906
- Pathways
- Glycosaminoglycan Metabolic Process
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