ADAM15 Protein (AA 207-452, Extracellular) (GST tag)
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- Target See all ADAM15 Proteins
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- Protein Type
- Recombinant
- Protein Characteristics
- Extracellular, AA 207-452
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ADAM15 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- DVVTETKTVE LVIVADHSEA QKYRDFQHLL NRTLEVALLL DTFFRPLNVR VALVGLEAWT QRDLVEISPN PAVTLENFLH WRRAHLLPRL PHDSAQLVTG TSFSGPTVGM AIQNSICSPD FSGGVNMDHS TSILGVASSI AHELGHSLGL DHDLPGNSCP CPGPAPAKTC IMEASTDFLP GLNFSNCSRR ALEKALLDGM GSCLFERLPS LPPMAAFCGN MFVEPGEQCD CGFLDDCVDP CCDSLT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product ADAM15 Protein
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ADAM Metallopeptidase Domain 15 (ADAM15) (AA 1-772) protein (GST tag)
ADAM15 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
ADAM Metallopeptidase Domain 15 (ADAM15) (AA 18-696) protein (Fc Tag)ADAM15 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ADAM Metallopeptidase Domain 15 (ADAM15) (Active) protein (His tag)ADAM15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
- Alternative Name
- ADA15 (ADAM15 Products)
- Background
- Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage rodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain
- Molecular Weight
- 54 kDa
- UniProt
- Q13444
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