Titin Protein (TTN) (AA 5398-5604, partial) (His tag)

Catalog No. ABIN5712956

Product Details

Target: Titin (TTN)

Protein Type: Recombinant

Protein Characteristics: AA 5398-5604, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Titin protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: VFKCSVIGIP TPEVKWYKEY MCIEPDNIKY VISEEKGSHT LKIRNVCLSD SATYRCRAVN CVGEAICRGF LTMGDSEIFA VIAKKSKVTL SSLMEELVLK SNYTDSFFEF QVVEGPPRFI KGISDCYAPI GTAAYFQCLV RGSPRPTVYW YKDGKLVQGR RFTVEESGTG FHNLFITSLV KSDEGEYRCV ATNKSGMAES FAALTLT

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: Titin (TTN)

Alternative Name: TITIN (TTN Products)

Background: Key component in the assbly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, ses to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.

Molecular Weight: 27.2 kDa

UniProt: Q8WZ42