GDF5 Protein (AA 376-495) (His tag)

Catalog No. ABIN5853985

Product Details

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Protein Type: Recombinant

Protein Characteristics: AA 376-495

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GDF5 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSAPLANRQ GKRPSKNLKA RCSRKALHVN FKDMGWDDWI IAPLEYEAFH CEGLCEFPLR SHLEPTNHAV IQTLMNSMDP ESTPPTCCVP TRLSPISILF IDSANNVVYK QYEDMVVESC GCR

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Alternative Name: GDF5 (GDF5 Products)

Background: Growth/differentiation factor 5 precursor, also known as GDF5, is a member of the TGF superfamily. GDF5 has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. GDF5mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs. Recombinant mouse GDF5 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 16kDa (143aa)

NCBI Accession: NP_032135

UniProt: P43027