IL-31 Protein (AA 24-159) (His tag)
-
- Target See all IL-31 (IL31) Proteins
- IL-31 (IL31) (Interleukin 31 (IL31))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-159
-
Origin
- Dog
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This IL-31 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQHHHH HH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product IL31 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- IL-31 (IL31) (Interleukin 31 (IL31))
- Alternative Name
- IL31 (IL31 Products)
- Background
- IL31, also known as interleukin 31, is a member of the gp130/interleukin-6 cytokine family that is produced by cell types such as T helper 2 lymphocytes and cutaneous lymphocyte antigen positive skin homing T cells. IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM R beta). The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN gamma on monocytes. Recombinant canine IL31, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 16.1kDa (142aa) 18-28kDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_001159386
-