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IL-31 Protein (AA 24-159) (His tag)

IL31 Origin: Dog Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Catalog No. ABIN5854872
  • Target See all IL-31 (IL31) Proteins
    IL-31 (IL31) (Interleukin 31 (IL31))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-159
    Origin
    • 12
    • 7
    • 4
    • 2
    • 1
    Dog
    Source
    • 16
    • 6
    • 2
    • 1
    Baculovirus infected Insect Cells
    Purification tag / Conjugate
    This IL-31 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQHHHH HH
    Purity
    > 95 % by SDS - PAGE
    Endotoxin Level
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product IL31 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    IL-31 (IL31) (Interleukin 31 (IL31))
    Alternative Name
    IL31 (IL31 Products)
    Background
    IL31, also known as interleukin 31, is a member of the gp130/interleukin-6 cytokine family that is produced by cell types such as T helper 2 lymphocytes and cutaneous lymphocyte antigen positive skin homing T cells. IL-31 signals via a heterodimeric receptor complex composed of a gp130 related molecule termed IL-31RA (also GPL and GLMR) and an Oncostatin M receptor (OSM R beta). The IL-31 receptor is constitutively expressed by keratinocytes and upregulated by IFN gamma on monocytes. Recombinant canine IL31, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molecular Weight
    16.1kDa (142aa) 18-28kDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_001159386
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