LAMP2 Protein (AA 29-375) (His tag)
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- Target See all LAMP2 Proteins
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-375
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This LAMP2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- ADPLELNLTD SENATCLYAK WQMNFTVRYE TTNKTYKTVT ISDHGTVTYN GSICGDDQNG PKIAVQFGPG FSWIANFTKA ASTYSIDSVS FSYNTGDNTT FPDAEDKGIL TVDELLAIRI PLNDLFRCNS LSTLEKNDVV QHYWDVLVQA FVQNGTVSTN EFLCDKDKTS TVAPTIHTTV PSPTTTPTPK EKPEAGTYSV NNGNDTCLLA TMGLQLNITQ DKVASVININ PNTTHSTGSC RSHTALLRLN SSTIKYLDFV FAVKNENRFY LKEVNISMYL VNGSVFSIAN NNLSYWDAPL GSSYMCNKEQ TVSVSGAFQI NTFDLRVQPF NVTQGKYSTA QDCSADDDNF HHHHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product LAMP2 Protein
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Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 30-127) protein (GST tag)
LAMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 34-231) protein (His-IF2DI Tag)LAMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 26-379) protein (His tag)LAMP2 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Lysosomal-Associated Membrane Protein 2 (LAMP2) protein (His tag)LAMP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
- Alternative Name
- LAMP2 (LAMP2 Products)
- Background
- LAMP2, also known as lysosome-associated membrane glycoprotein 2 isoform A, is a major component of lysosomal membranes. It provides selectins with carbohydrate ligands. This protein mediates the lysosomal uptake of the chaperone HSC73 in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles. Deficiency of LAMP2 is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. Recombinant human LAMP2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 39.4kDa (356aa) 57-70KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_002285
- UniProt
- P13473
- Pathways
- Autophagy
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