DNER Protein (AA 29-637, Extracellular Domain) (Fc Tag)
DNER
Origin: Human
Host: HEK-293 Cells
Recombinant
>90 % (SDS-PAGE)
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- Target See all DNER Proteins
- DNER (delta/notch-Like EGF Repeat Containing (DNER))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-637, Extracellular Domain
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DNER protein is labelled with Fc Tag.
- Purpose
- DNER (extracellular domain) (human):Fc (human) (rec.)
- Specificity
- The extracellular domain of human DNER (aa 29-637) is fused at the C-terminus to the Fc portion of human IgG1.
- Cross-Reactivity
- Human
- Characteristics
- The extracellular domain of human DNER (aa 29-637) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- Sterile filtered
- Endotoxin Level
- <0.06EU/μg purified protein (LAL test).
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized from 0.2μm-filtered solution in PBS.
- Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
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- Target
- DNER (delta/notch-Like EGF Repeat Containing (DNER))
- Alternative Name
- DNER (DNER Products)
- Background
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BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor
DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
- Molecular Weight
- ~120kDa (SDS-PAGE)
- NCBI Accession
- NP_620711
- Pathways
- Skeletal Muscle Fiber Development
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