Crk Protein (AA 1-204) (His tag)
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- Target See all Crk (CRK) Proteins
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-204
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Crk protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CRK, 1-204aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CRK Protein
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V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-224) protein (His tag)
CRK Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (AA 1-204) protein (GST tag)CRK Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CRK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CRK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol
- Storage
- 4 °C
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- Target
- Crk (CRK) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
- Alternative Name
- CRK (CRK Products)
- Background
- CRK is a member of signaling adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein is involved in many cellular processes including apoptosis, proliferation, and differentiation. It has a modular domain architecture consisting of an SH2 followed by two SH3 domains (src-homology domains). The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Recombinant human CRK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Adapter molecule crk, Proto-oncogene c-Crk, p38, CRKII. NCBI no.: NP_005197
- Molecular Weight
- 25.0 kDa (224aa), confirmed by MALDI-TOF
- Pathways
- Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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