SIRT2 Protein (AA 1-352) (His tag)
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- Target See all SIRT2 Proteins
- SIRT2 (Sirtuin 2 (SIRT2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-352
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SIRT2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- SIRT2, 1-352aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SIRT2 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 2mM DTT, 200mM NaCl, 0.5mM EDTA
- Storage
- 4 °C
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- Target
- SIRT2 (Sirtuin 2 (SIRT2))
- Alternative Name
- SIRT2 (SIRT2 Products)
- Background
- SIRT2 (NAD-dependent deacetylase sirtuin-2) is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. SIRT2 is a NAD-dependent deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Recombinant human SIRT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NAD-dependent deacetylase sirtuin-2, SIR2, SIR2L, SIR2L2. NCBI no.: NP_085096
- Molecular Weight
- 41.7kDa (372aa), confirmed by MALDI-TOF
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