TFPI2 Protein (AA 23-213) (His tag)
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- Target See all TFPI2 Proteins
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-213
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Origin
- Human
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This TFPI2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- DAAQEPTGNN AEICLLPLDY GPCRALLLRY YYDRYTQSCR QFLYGGCEGN ANNFYTWEAC DDACWRIEKV PKVCRLQVSV DDQCEGSTEK YFFNLSSMTC EKFFSGGCHR NRIENRFPDE ATCMGFCAPK KIPSFCYSPK DEGLCSANVT RYYFNPRYRT CDAFTYTGCG GNDNNFVSRE DCKRACAKAL KLEHHHHHH
- Purity
- > 95 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
- Alternative Name
- TFPI2 (TFPI2 Products)
- Synonyms
- MGC68843 Protein, TFPI2 Protein, MGC108301 Protein, si:ch211-262k23.2 Protein, tfpi2 Protein, PP5 Protein, REF1 Protein, TFPI-2 Protein, AV000670 Protein, PP5/TFPI-2 Protein, tissue factor pathway inhibitor 2 L homeolog Protein, tissue factor pathway inhibitor 2 Protein, tfpi2.L Protein, TFPI2 Protein, tfpi2 Protein, Tfpi2 Protein
- Background
- TFPI2, as known as tissue factor pathway inhibitor 2 isoform 1, is a kunitz-type serine proteinase inhibitor, which is produced and secreted into endothelial cell matrix (ECM) by endothelial cells, smooth muscle cells, fibroblasts, keratinocytes, and urothelium. Also, this protein has been shown to inhibit ECM proteases essential for angiogenesis and metastasis. Recombinant human TFPI2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 22.9kDa (199aa) 18-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_006519
- UniProt
- P48307