CPI-17 Protein (AA 1-147) (His tag)
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- Target See all CPI-17 (PPP1R14A) Proteins
- CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-147
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CPI-17 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PPP1R14A , 1-147aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PPP1R14A Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid in 20mM Tris pH 8.0, 2mM EDTA, 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
- Alternative Name
- PPP1R14A (PPP1R14A Products)
- Background
- PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization. Recombinant His tagged PPP1R14A was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CPI17, CPI-17, PPP1INL, Protein phosphatase 1, regulatory (inhibitor) subunit 14A, PPP1R14A , Protein phosphatase 1, regulatory (inhibitor) subunit 14A CPI 17, CPI 17 alpha, CPI 17alpha, CPI17, PKC potentiated inhibitory protein of PP1, Protein phosphatase 1 regulatory (inhibitor) subunit 14A, Protein phosphatase 1 regulatory subunit 14A, Regulatory subunit 14A,. NCBI no.: NP_150281
- Molecular Weight
- 18 kDa (167 aa), confirmed by MALDI-TOF.
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