MAT1A Protein (AA 1-395) (His tag)
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- Target See all MAT1A Proteins
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-395
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MAT1A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- MAT1A, 1-395aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product MAT1A Protein
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Methionine Adenosyltransferase I, alpha (MAT1A) (AA 1-395) protein (His tag)
custom-made MAT1A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Methionine Adenosyltransferase I, alpha (MAT1A) (AA 215-395) protein (His-IF2DI Tag)MAT1A Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Methionine Adenosyltransferase I, alpha (MAT1A) (AA 1-395) protein (GST tag)MAT1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Methionine Adenosyltransferase I, alpha (MAT1A) (AA 1-396) protein (His tag)custom-made MAT1A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M NaCl, 10% glycerol
- Storage
- 4 °C
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- Target
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- Alternative Name
- MAT1A (MAT1A Products)
- Background
- MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFkappaB and TNFalpha cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth. Recombinant human MAT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: MAT, MATA1, SAMS, SAMS1, methionine adenosyltransferase I alpha, S-adenosylmethionine synthetase, MAT1A,. NCBI no.: NP_000420
- Molecular Weight
- 45.6 kDa (414aa), confirmed by MALDI-TOF.
- Pathways
- Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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