TOLLIP Protein (AA 1-274) (His tag)
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- Target See all TOLLIP Proteins
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-274
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TOLLIP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TOLLIP, 1-274aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TOLLIP Protein
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Toll Interacting Protein (TOLLIP) (AA 2-274) protein (GST tag)
TOLLIP Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Toll Interacting Protein (TOLLIP) (AA 1-274) protein (GST tag)TOLLIP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Toll Interacting Protein (TOLLIP) protein (Myc-DYKDDDDK Tag)TOLLIP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Toll Interacting Protein (TOLLIP) proteinTOLLIP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.2M NaCl,2mM DTT
- Storage
- 4 °C
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- Target
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Alternative Name
- TOLLIP (TOLLIP Products)
- Background
- TOLLIP, also known as Toll interacting protein, is an inhibitory adaptor protein within Toll-like receptors. The TLR pathway is a part of the innate immune system that recognizes structurally conserved molecular patterns of microbial pathogens, leading to an inflammatory immune response. Negative regulation of TLR signaling by TOLLIP may limit the production of proinflammatory mediators during inflammation and infection. Also, it forms a complex with Tom1 to regulate endosomal trafficking of ubiquitinated proteins. Recombinant human TOLLIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Toll interacting protein, FLJ33531, IL-1RAcPIP. NCBI no.: NP_061882
- Molecular Weight
- 32.4 kDa (294aa) confirmed by MALDI-TOF
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