HMGB2 Protein (AA 1-209) (His tag)

Catalog No. ABIN667939

Product Details

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Protein Type: Recombinant

Protein Characteristics: AA 1-209

Origin: Human

Source: Hi-5 Cells

Purification tag / Conjugate: This HMGB2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: HMGB2, 1-209aa, Human, His tag, Baculovirus

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Storage: 4 °C

Target Details

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Alternative Name: HMGB2 (HMGB2 Products)

Background: High mobility group protein B2, also known as HMGB2, is a member of the non-histone chromosomal high-mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Recombinant human HMGB2 protein, fused to His-tag at N-terminus, was expressed in Baculovirus and purified by using conventional chromatography techniques. Synonyms: High mobility group protein B2, HMG2. NCBI no.: NP_002120

Molecular Weight: 26.4 kDa (232aa)

Pathways: Cellular Response to Molecule of Bacterial Origin