DCPS Protein (AA 1-337) (His tag)
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- Target See all DCPS Proteins
- DCPS (Decapping Enzyme, Scavenger (DCPS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-337
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DCPS protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- DCPS, 1-337aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DCPS Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- Storage
- 4 °C
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- Target
- DCPS (Decapping Enzyme, Scavenger (DCPS))
- Alternative Name
- DCPS (DCPS Products)
- Background
- DCPS, also known as scavenger mRNA-decapping enzyme, is belongs to the HIT family. It is necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. A scavenger decapping enzyme, DcpS was shown to hydrolyze the residual m7GpppN cap structure after the complete 3'-5' degradation of the mRNA by the exosome. DcpS releases m7GMP and is unable to cleave cap structures attached to a long RNA chain. Recombinant human DCPS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Scavenger mRNA-decapping enzyme DcpS, DCS1, HINT5. NCBI no.: NP_054745
- Molecular Weight
- 40.8 kDa (357aa), confirmed by MALDI-TOF
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