PAPSS1 Protein (AA 24-624) (His tag)

Catalog No. ABIN668017

Product Details

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Protein Type: Recombinant

Protein Characteristics: AA 24-624

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PAPSS1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: PAPSS1, 24-624aa, Human, His tag, E.coli

Purity: > 85 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl

Storage: 4 °C

Target Details

Target: PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

Alternative Name: PAPSS1 (PAPSS1 Products)

Background: PAPSS1, also known as bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, is a bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway, yielding 3'-phosphoadenylylsulfate (PAPS). PAPSS1 is also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells. Recombinant human PAPSS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1, ATPSK1, PAPSS, SK1. NCBI no.: NP_005434

Molecular Weight: 70.9 kDa (626aa)

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process