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PAPSS1 Products

(3'-phosphoadenosine 5'-phosphosulfate Synthase 1 (PAPSS1))

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Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008].

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Featured PAPSS1 Categories

PAPSS1 Antibodies

High quality antibodies with extensive validation data.

PAPSS1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAPSS1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (4)
Cat. No. ABIN2855665
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF, RNAi
Validations
  • (4)
Cat. No. ABIN563926
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (6)
  • (1)
Cat. No. ABIN1882107
Quantity 400 μL
Datasheet Datasheet

Recommended PAPSS1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6201023
Quantity 96 tests
Datasheet Datasheet

Recommended PAPSS1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313978
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313976
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094375
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PAPSS1 products

Gillies, Lee, Long, Ktistakis, Pyne, Pyne: "The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: possible role in regulating cell division." in: Cellular signalling, Vol. 21, Issue 5, pp. 675-84, (2009) (PubMed).

Bergelin, Blom, Heikkilä, Löf, Alam, Balthasar, Slotte, Hinkkanen, Törnquist: "Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on protein kinase C-alpha and ERK1/2." in: Endocrinology, Vol. 150, Issue 5, pp. 2055-63, (2009) (PubMed).

Lansdon, Fisher, Segel: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains." in: Biochemistry, Vol. 43, Issue 14, pp. 4356-65, (2004) (PubMed).

Venkatachalam: "Human 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase: biochemistry, molecular biology and genetic deficiency." in: IUBMB life, Vol. 55, Issue 1, pp. 1-11, (2003) (PubMed).

Fuda, Shimizu, Lee, Akita, Strott: "Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms." in: The Biochemical journal, Vol. 365, Issue Pt 2, pp. 497-504, (2002) (PubMed).

Xu, Otterness, Freimuth, Carlini, Wood, Mitchell, Moon, Kim, Xu, Siciliano, Weinshilboum: "Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization." in: Biochemical and biophysical research communications, Vol. 268, Issue 2, pp. 437-44, (2000) (PubMed).

Venkatachalam, Akita, Strott: "Molecular cloning, expression, and characterization of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase and its functional domains." in: The Journal of biological chemistry, Vol. 273, Issue 30, pp. 19311-20, (1998) (PubMed).

Faiyaz ul Haque, King, Krakow, Cantor, Rusiniak, Swank, Superti-Furga, Haque, Abbas, Ahmad, Ahmad, Cohn: "Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse." in: Nature genetics, Vol. 20, Issue 2, pp. 157-62, (1998) (PubMed).

Girard, Baekkevold, Amalric: "Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetase." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 12, Issue 7, pp. 603-12, (1998) (PubMed).

Synonyms and alternative names related to PAPSS1

3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1), 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (Papss1), 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (papss1), 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (papss1.L), bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (LOC100543301), bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (LOC100637112), PAPS synthetase (Papss), AI325286, Asapk, ATPSK1, atpsk1, CG8363, Dmel\\CG8363, DmPAPSS, l(3)76BDn, MGC82588, PAPS, Paps, paps, PAPSS, papss, papss1, PAPSS1, SK1, sk1, wu:fc43e12, zgc:194984, zgc:194985

Protein level used designations for PAPSS1

  • 3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 1
  • PAPS synthase 1
  • PAPSS 1
  • SK 1
  • bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1
  • sulfurylase kinase 1
  • 3'-phosphoadenosine 5'-phosphosulfate synthase 1
  • SK1
  • bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1-like
  • CG8363-PA
  • CG8363-PB
  • CG8363-PC
  • CG8363-PD
  • CG8363-PE
  • CG8363-PF
  • CG8363-PG
  • CG8363-PH
  • PAPs synthase
  • Papss-PA
  • Papss-PB
  • Papss-PC
  • Papss-PD
  • Papss-PE
  • Papss-PF
  • Papss-PG
  • Papss-PH
  • paps synthetase
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