C5AR1 Protein (AA 1-37) (Fc Tag)
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- Target See all C5AR1 Proteins
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-37
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This C5AR1 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human C5AR1 Protein with C-terminal human Fc tag
- Specificity
- C5AR1 (Met1-Asp37) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product C5AR1 Protein
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Complement Component 5a Receptor 1 (C5AR1) protein
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Complement Component 5a Receptor 1 (C5AR1) protein (Myc-DYKDDDDK Tag)C5AR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Alternative Name
- C5AR1 (C5AR1 Products)
- Background
- Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
- Molecular Weight
- predicted molecular mass of 30.4 kDa after removal of the signal peptide.The apparent molecular mass of C5AR1-hFc is 40-53 kDa due to glycosylation.
- UniProt
- P21730
- Pathways
- Complement System
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