SARS-CoV-2 Spike S2 Protein (P.1 - gamma) (His tag)

Catalog No. ABIN6992375

Product Details

Target: SARS-CoV-2 Spike S2

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: P.1 - gamma

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma

Source: HEK-293 Cells

Purification tag / Conjugate: This SARS-CoV-2 Spike S2 protein is labelled with His tag.

Purpose: SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag

Sequence: AA 686-1213

Characteristics: SARS-CoV-2 S2 protein (T1027I, V1176F), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The T1027I/ V1176F mutations were identified in the SARS-CoV-2 variant (known as P.1) which emerged in Brazil.

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: SARS-CoV-2 Spike S2

Alternative Name: SARS-CoV-2 S2 protein (SARS-CoV-2 Spike S2 Products)

Target Type: Viral Protein

Background: The ongoing SARS-COV-2 pandemics has sickened 3.7 million people around the world, claiming over 1,000,000 lives. To deal with this global public health crisis, unprecedented efforts are being made to study the virus, SARS-CoV-2. At present, there are 193 new crown vaccine projects registered with the World Health Organization are being developed. To support these studies, ACRO has developed Mouse Anti-SARS-CoV-2 antibody IgG Serologic Assay kit.

Molecular Weight: 59.9 kDa