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SARS-CoV-2 Spike S2 Protein (B.1.351 - beta) (His tag)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6992376
  • Target See all SARS-CoV-2 Spike S2 Proteins
    SARS-CoV-2 Spike S2
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    B.1.351 - beta
    Origin
    • 15
    • 3
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta
    Source
    • 13
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SARS-CoV-2 Spike S2 protein is labelled with His tag.
    Purpose
    SARS-CoV-2 S2 protein (A701V), His Tag
    Sequence
    AA 686-1213
    Characteristics
    SARS-CoV-2 S2 protein (A701V), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The A701V mutation was identified in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in South Africa.
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    SARS-CoV-2 Spike S2
    Alternative Name
    SARS-CoV-2 S2 protein (SARS-CoV-2 Spike S2 Products)
    Synonyms
    E2 Protein, Surface Glycoprotein Protein, S Protein
    Target Type
    Viral Protein
    Background
    The ongoing SARS-COV-2 pandemics has sickened 3.7 million people around the world, claiming over 1,000,000 lives. To deal with this global public health crisis, unprecedented efforts are being made to study the virus, SARS-CoV-2. At present, there are 193 new crown vaccine projects registered with the World Health Organization are being developed. To support these studies, ACRO has developed Mouse Anti-SARS-CoV-2 antibody IgG Serologic Assay kit.
    Molecular Weight
    59.8 kDa
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