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SARS-CoV-2 Spike S2 Protein (SARS-CoV-2 S2) (B.1.351 - beta) (His tag)

This Recombinant SARS-CoV-2 Spike S2 protein is produced in HEK-293 Cells.
Catalog No. ABIN6992376
$372.31
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Quick Overview for SARS-CoV-2 Spike S2 Protein (SARS-CoV-2 S2) (B.1.351 - beta) (His tag) (ABIN6992376)

Target

See all SARS-CoV-2 Spike S2 (SARS-CoV-2 S2) Proteins
SARS-CoV-2 Spike S2 (SARS-CoV-2 S2)

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 22
  • 3
  • 1
  • 1
  • 1
SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta

Source

  • 15
  • 4
  • 3
  • 1
HEK-293 Cells

Purity

>95 % as determined by SDS-PAGE.
  • Protein Characteristics

    B.1.351 - beta

    Purification tag / Conjugate

    This SARS-CoV-2 Spike S2 protein is labelled with His tag.

    Purpose

    SARS-CoV-2 S2 protein (A701V), His Tag

    Sequence

    AA 686-1213

    Characteristics

    SARS-CoV-2 S2 protein (A701V), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The A701V mutation was identified in the SARS-CoV-2 variant (known as B.1.351 or 20C/501Y.V2) which emerged in South Africa.

    Endotoxin Level

    Less than 1.0 EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C
  • Target

    SARS-CoV-2 Spike S2 (SARS-CoV-2 S2)

    Alternative Name

    SARS-CoV-2 S2 protein

    Target Type

    Viral Protein

    Background

    The ongoing SARS-COV-2 pandemics has sickened 3.7 million people around the world, claiming over 1,000,000 lives. To deal with this global public health crisis, unprecedented efforts are being made to study the virus, SARS-CoV-2. At present, there are 193 new crown vaccine projects registered with the World Health Organization are being developed. To support these studies, ACRO has developed Mouse Anti-SARS-CoV-2 antibody IgG Serologic Assay kit.

    Molecular Weight

    59.8 kDa
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