CD84 Protein (CD84) (AA 22-220) (His tag)
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- Target See all CD84 Proteins
- CD84
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-220
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CD84 protein is labelled with His tag.
- Purpose
- Recombinant Human SLAMF5/CD84 Protein (aa 22-220, His Tag)
- Sequence
- Lys22-Arg220
- Characteristics
- Recombinant Human SLAM Family Member 5 is produced by our Mammalian expression system and the target gene encoding Lys22-Arg220 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD84 Protein
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CD84 (CD84) (AA 22-225) protein (His-Avi Tag)
CD84 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD84 (CD84) protein (His tag)CD84 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
CD84 (CD84) (AA 22-225) protein (mFc-His Tag)CD84 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD84 (CD84) protein (His tag)CD84 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % by SDS - PAGE SDS
CD84 (CD84) (AA 1-328) protein (GST tag)CD84 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
CD84 (CD84) (AA 22-221) protein (Fc Tag)CD84 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD84 (CD84) (Active) protein (His tag)CD84 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD84
- Alternative Name
- SLAMF5/CD84 (CD84 Products)
- Background
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Background: SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature human CD84 consists of a 204 amino acid (aa) extracellular domain (ECD) with two Iglike domains,a 21 aa transmembrane segment, and a 99 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs (ITSMs). CD84 exhibits homophilic binding which is mediated by the N-terminal Ig-like domain. Ligation induces tyrosine phosphorylation in the cytoplasmic ITSMs which then recruit the signaling adaptor molecules SAP (SLAM-associated protein) and EAT-2(EWS/Fli1-activated transcript 2).CD84 signaling inhibits Fc epsilon RI-induced mast cell activation but enhances platelet activation. LPS-induced macrophage activation,T cell proliferation and IFN-γproduction, and the interactions between T cells and B cells that are required for germinal center formation.
Synonym: SLAM family member 5, Cell surface antigen MAX.3, Hly9-beta, Leukocyte differentiation antigen CD84, Signaling lymphocytic activation molecule 5, CD84, SLAMF5,hCD84,LY9B,mCD84
- Molecular Weight
- 23.1 kDa
- UniProt
- Q9UIB8
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