Quick Overview for CD84 Protein (CD84) (His tag) (ABIN7320156)
Target
See all CD84 ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CD84 protein is labelled with His tag.
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Purpose
- Recombinant Mouse SLAMF5/CD84 Protein (His Tag)
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Sequence
- Met 1-Val 221
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Characteristics
- A DNA sequence encoding the mouse CD84 isoform 1 (Q18PI6-1) extracellular domain (Met 1-Val 221) was expressed, with a polyhistidine tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to bind biotinylated recombinant human SH2D1A in a functional ELISA.
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CD84 (CD84) (AA 22-225) (Active) protein (His-Avi Tag)
CD84 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
CD84 (CD84) (AA 22-225) protein (His tag,mFc Tag)CD84 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD84 (CD84) (AA 22-221) protein (Fc Tag)CD84 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
CD84 (CD84) (AA 22-225) protein (His tag)CD84 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS
CD84 (CD84) (AA 22-223) protein (His tag)CD84 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
CD84 (CD84) (AA 1-328) protein (GST tag)CD84 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- CD84
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Alternative Name
- SLAMF5/CD84
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Background
- CD84,CD84 antigen,CD84 Molecule,Cd84,Leukocyte differentiation antigen CD84,Ly-9B,SLAM family member 5,SLAMF5,Signaling lymphocytic activation molecule 5,The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
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Molecular Weight
- 24 kDa
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Gene ID
- 12523
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UniProt
- Q18PI6
Target
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