FBP1 Protein (His tag)
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- Target See all FBP1 Proteins
- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This FBP1 protein is labelled with His tag.
- Purpose
- Recombinant Human FBPase 1/FBP1 Protein (Human Cells, His Tag)
- Sequence
- Ala2-Gln338
- Characteristics
- Recombinant Human Fructose-1,6-Bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product FBP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,200 mM NaCl,1 mM DTT,10 % Glycerol, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
- Alternative Name
- FBPase 1/FBP1 (FBP1 Products)
- Background
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Background: Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis, gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.
Synonym: Fructose-1,6-bisphosphatase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,FBP,FBPase 1
- Molecular Weight
- 37.8 kDa
- UniProt
- P09467
- Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport
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