FBP1 Protein (His tag)

Catalog No. ABIN7319228

Product Details

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This FBP1 protein is labelled with His tag.

Purpose: Recombinant Human FBPase 1/FBP1 Protein (E. coli, His Tag)

Sequence: Ala2-Gln338

Characteristics: Recombinant Human Fructose-1,6-Bisphosphatase 1 is produced by our E.coli expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20 % Glycerol, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Alternative Name: FBPase 1/FBP1 (FBP1 Products)

Synonyms: FBP Protein, Fbp-2 Protein, Fbp2 Protein, Fbp3 Protein, FBP1 Protein, fbp2 Protein, Fdp Protein, CG10611 Protein, CG31692 Protein, Dmel\\CG31692 Protein, FbPase Protein, fbp1 Protein, cb598 Protein, fb57b01 Protein, zgc:64127 Protein, id:ibd1091 Protein, wu:fb17g10 Protein, wu:fb57b01 Protein, fdp Protein, xcc-b100_0105 Protein, fbp1l Protein, fk92h02 Protein, wu:fk92h02 Protein, zgc:64096 Protein, fbp Protein, fbp1.S Protein, fructose-bisphosphatase 1 Protein, fructose bisphosphatase 1 Protein, Fructose-1,6-bisphosphatase Protein, fructose-1,6-bisphosphatase Protein, fructose-1,6-bisphosphatase 1 Protein, fructose-bisphosphatase class I Protein, fructose-1,6-bisphosphatase 1b Protein, fbp Protein, fructose-1,6-bisphosphatase 1a Protein, fructose-bisphosphatase 1 L homeolog Protein, FBP1 Protein, Fbp1 Protein, fbp1 Protein, LOC100136618 Protein, RR_RS07410 Protein, fbp Protein, fbp1b Protein, fbp1a Protein, fbp1.L Protein

Background:

Background: Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

Synonym: Fructose-1,6-Bisphosphatase 1, FBPase 1, D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP

Molecular Weight: 37.9 kDa

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport